Oxycodone is classified as a Schedule II drug by the US Food and Drug Administration (FDA), which means it has a high potential for addition and abuse. In comparison, Tramadol is classified as a Schedule IV drug, which means it has a lower potential for abuse and a lower risk for dependence.
Both oxycodone and tramadol are prescribed for the management of acute and chronic moderate to severe pain.
Common side effects of oxycodone and tramadol include:
Some of the serious side effects and adverse events are different for oxycodone and tramadol. For example, oxycodone should be used cautiously in the elderly, debilitated patients, and in patients with serious lung disease because it can depress (slow) breathing. Some patients who received tramadol had seizures, and it may cause serotonin syndrome when combined with other drugs that increase serotonin.
Both oxycodone and tramadol are habit-forming, and patients may become addicted to the drug. If these drugs are discontinued abruptly, withdrawal symptoms may occur. Symptoms of withdrawal include: